For the ones in ecc/ed25519/ and ecc/ed448/ you will need at least OpenVPN 2.4.3 and at least OpenSSL 1.1.1
These configuration files are focused more on security than compatibility.
They work with OpenVPN 2.4.0 through 2.4.7, and OpenSSL 1.0.1d through 1.1.1b
Like the rsa configs, the level of security depends on the version of OpenVPN/OpenSSL you have.
The newer the version, the better the security.
If necessary, you can change the port in these configs to anything from 1 to 29999,
excluding ports 5061 and 5062. Those two are reserved for the Ed25519 and Ed448 configs,
and ports 30000-65535 are reserved for port forwarding.